The surprising role of gut infection in Alzheimer's disease

Researchers have discovered a surprising link between a chronic gut infection caused by a common virus and the development of Alzheimer's disease in a subset of people. It is believed most humans are exposed to this virus -- called cytomegalovirus or HCMV -- during the first few decades of life. According to the new research, in some people, the virus may linger in an active state in the gut, where it may travel to the brain via the vagus nerve -- a critical information highway that connects the gut and brain. Once there, the virus can change the immune system and contribute to other changes associated with Alzheimer's disease. This virus may be a target for antiviral treatments.


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Study finds slowing of age-related declines in older adults

A new study reveals significant improvements in the health of older adults when compared to previous generations.


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AI may help researchers with medical chart review, study finds

Researchers trained a large language model to read medical charts, looking for signs that kids with ADHD received the right follow-up care when using new medications.


http://dlvr.it/TH2XxR

Hair growth drug safe at low doses for breast cancer patients

Oral minoxidil is a commonly prescribed treatment for hair loss. The drug is also the active ingredient in over-the-counter Rogaine. The prescription treatment is known, however, to dilate blood vessels, and experts worry that this could increase the heart-related side effects of chemotherapy and lead to chest pain, shortness of breath, or fluid buildup. Now, a study in women with breast cancer suggests that low oral doses of minoxidil, taken during or after cancer treatment, appear to regrow hair in most patients and without causing any serious heart-related side effects that require additional therapies or hospitalization.


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Study finds slowing of age-related declines in older adults

A new study reveals significant improvements in the health of older adults when compared to previous generations.


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3 Things to Do While Visiting Aging Parents for the Holidays

Take advantage of your holiday visit to check on older adults During the holidays, many people will be visiting aging parentsRead More


The post 3 Things to Do While Visiting Aging Parents for the Holidays appeared first on DailyCaring.


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New recommendations to increase transparency and tackle potential bias in medical AI technologies

A new set of recommendations aims to help improve the way datasets are used to build Artificial intelligence (AI) health technologies and reduce the risk of potential AI bias.


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Almost three quarters of adolescents experience depression or anxiety

Almost three quarters of adolescents in Australia experience clinically significant depression or anxiety symptoms, with most being chronic, according to a new study. And preventive strategies outside our clinics are urgently required to address this considerable public health problem facing the nation.


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Sleep apnea linked to changes in the brain

People with breathing problems during sleep may have a larger hippocampus, the area of the brain responsible for memory and thinking, according to a new study. The study, which included mostly Latino people, also found that those with lower oxygen levels during sleep had changes in the deep parts of the brain, the white matter, a common finding of decreased brain health that develops with age.


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3 Fun Games for Seniors with Dementia Improve Quality of Life

Activities for people with dementia bring happier days Keeping seniors with Alzheimer’s disease or dementia engaged, happily occupied, and inRead More


The post 3 Fun Games for Seniors with Dementia Improve Quality of Life appeared first on DailyCaring.


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Poor vascular health accelerates brain aging

Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.


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Antibody that neutralizes inhibitory factors involved in nerve regeneration leads to enhanced motor function after acute spinal cord injury

Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers have investigated this with promising results. For the first time, it was possible to identify patient groups that displayed a clinically relevant treatment effect.


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First successful clinical trial of VU319 brings Alzheimer's treatment one step closer

Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials.


http://dlvr.it/TGxP79

First successful clinical trial of VU319 brings Alzheimer's treatment one step closer

Phase I clinical trial of a drug was successfully completed, with promise to treat Alzheimer's and other neurodegenerative diseases. The compound, named VU319, is the first end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials.


http://dlvr.it/TGwzwN

Atrial fibrillation: A review

In the U.S., atrial fibrillation (AF), a heart condition that causes an irregular heartbeat in the upper chambers of the heart, affects up to one in three people in their lifetime. Significant complications associated with this condition include ischemic stroke, heart failure, myocardial infarction, chronic kidney disease, dementia and mortality. In a new review article scientists summarize the current evidence regarding the epidemiology, pathophysiology, diagnosis and management of AF.


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Poor vascular health accelerates brain aging

Using an AI tool, researchers have analyzed brain images from 70-year-olds and estimated their brains' biological age. They found that factors detrimental to vascular health, such as inflammation and high glucose levels, are associated with an older-looking brain, while healthy lifestyles were linked to brains with a younger appearance.


http://dlvr.it/TGwbkV

Getting a grip on health norms: Handgrip strength

A groundbreaking study has created the world's largest and most geographically comprehensive international norms for handgrip strength, enabling global peer-comparison, health screening and surveillance across the adult lifespan.


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Biased language in clinical handoffs may negatively impact patient care

A new study shows that when clinicians hear a patient described with negatively biased language, they develop less empathy towards the patient and, in some cases, become less accurate in recalling the patient's critical health details.


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Study supports new blood-based biomarker to detect early brain changes leading to cognitive impairment and dementia

To identify and follow blood vessel-related changes in the brain that contribute to cognitive impairment and dementia, researchers and clinicians typically rely on MRI to evaluate 'downstream' biological markers -- those at the end of a cascade of events. But a new multicenter study could lead to a cost-effective blood test to identify changes occurring near the top of the chain, potentially identifying at-risk patients at an earlier stage.


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Diagnosing and managing blast injuries

The prevalence of armed conflicts, terrorist attacks and industrial accidents necessitates clinician understanding of blast injuries in both civilian and military settings. Blast injuries are a complex form of trauma, resulting from the explosive release of energy. The severity and types of injury depend on the proximity to the blast, blast pressure and the presence of other elements like fragments and heat.


http://dlvr.it/TGth3y

Hidden fat predicts Alzheimer's 20 years ahead of symptoms

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a new study. The researchers emphasized that lifestyle modifications targeted at reducing this fat could influence the development of Alzheimer's disease.


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Study finds lower rates of death from Alzheimer's disease among taxi and ambulance drivers

A new study raises the possibility that jobs that require frequent spatial processing -- such as figuring out a taxi route or the best way to navigate to a hospital -- could lead to lower rates of death from Alzheimer's disease. Researchers investigated this possibility by using national data on the occupations of people who had died to evaluate risk of death from Alzheimer's disease across 443 professions. They found that taxi driving and ambulance driving were associated with a lower rate of death from Alzheimer's disease compared to other professions.


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What motivates Americans to eat less red meat?

Limiting red meat consumption is key to a sustainable and healthy diet, yet Americans are among the world's largest consumers of red meat. A new study reveals the demographics of American adults who choose not to eat red meat and finds that environmental concerns may matter more to them than health risks.


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TV Show about Caring for Aging Parents: Ruth & Erica

You’ll relate to this TV series about caregiving and aging Caring for an older adult can be an isolating experience.Read More


The post TV Show about Caring for Aging Parents: Ruth & Erica appeared first on DailyCaring.


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Potential epigenetic biomarker found for preeclampsia in pregnancy

Analysis of cheek swabs taken from pregnant women revealed a potential epigenetic biomarker for preeclampsia, a potentially life-threatening condition that often leads to preterm births. While a clinical trial is needed to confirm the results, a study offers hope that a simple test can be developed to identify preeclampsia earlier in pregnancy. Currently preeclampsia is usually identified by symptoms, such as abnormally high blood pressure, which only appear in the second trimester of pregnancy. Sometimes the condition can go undetected until it becomes an emergency.


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The global divide between longer life and good health

People around the globe are living longer -- but not necessarily healthier -- lives, according to new research. A study of 183 World Health Organization (WHO) member countries found those additional years of life are increasingly fraught with disease.


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25 Quick Journal Prompts That Reduce Caregiver Stress and Improve Health

Journaling is a fast track to stress reduction Caring for an older adult is stressful and can easily wear youRead More


The post 25 Quick Journal Prompts That Reduce Caregiver Stress and Improve Health appeared first on DailyCaring.


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Ditch TV and read a book: Research delivers best moves to reduce dementia risk

It's that time of the year when most of us get the chance to sit back and enjoy some well-deserved down time. But whether you reach for the TV controller, or a favorite book, your choice could have implications for your long-term brain health, say researchers.


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Rotavirus vaccine is safe for use in NICU babies, study suggests

Researchers found that transmission of rotavirus vaccine strains in a neonatal intensive care unit (NICU) is rare and without clinical consequences, strongly suggesting that giving the rotavirus vaccine to eligible infants during their hospitalization provides immune benefits that outweigh any risks. The findings could serve as the basis for a change in clinical practice.


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Mouse study captures aging process at the cellular level

As muscles age, their cells lose the ability to regenerate and heal after injury. Now, researchers have created the most comprehensive portrait to date of how that change, in mice, unfolds over time.


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Top 25 Senior Gift Ideas Under $25

Date published: 2024-12-12 Get 25 fantastic and affordable gift ideas Finding a wonderful gift for your older adult that’s alsoRead More


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Common brain network links brain atrophy patterns seen in schizophrenia

A new study has identified a unique brain network that links varied patterns of brain atrophy, or shrinkage, associated with schizophrenia.


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Research study shows the cost-effectiveness of AI-enhanced heart failure screening

Earlier research showed that primary care clinicians using AI-ECG tools identified more unknown cases of a weak heart pump, also called low ejection fraction, than without AI. New study findings suggest that this type of screening is also cost-effective in the long term, especially in outpatient settings.


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4 Ways to Help Seniors with Alzheimer’s Enjoy the Holidays

Holidays are often stressful for seniors with Alzheimer’s Holidays bring a flurry of activity, changes in daily routine, conversations withRead More


The post 4 Ways to Help Seniors with Alzheimer’s Enjoy the Holidays appeared first on DailyCaring.


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Generic platinum chemotherapy shortages did not increase deaths

An analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023.


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World's most common heart valve disease linked to insulin resistance in large national study

A large new population study of men over 45 indicates insulin resistance may be an important risk factor for the development of the world's most common heart valve disease -- aortic stenosis (AS).


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8 Wonderful Last Minute Gifts for Seniors

Date published: 2024-12-4 Get great gifts at local retailers It’s almost too late to get holiday gifts shipped! If you’reRead More


The post 8 Wonderful Last Minute Gifts for Seniors appeared first on DailyCaring.


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Social factors affect pediatric cardiac arrest outcomes

The odds on whether a child survives a cardiac arrest may depend on where they live, according to a new study from the University of Missouri School of Medicine.


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Ketone bodies: More than energy, they are powerful signaling metabolites that clean up damaged proteins

Ketone bodies are not just about energy. These metabolites are powerful signaling molecules that have profound effects on the proteome and protein quality control in the brain. Scientists, working in mouse models of Alzheimer's disease and aging, and in the nematode C. elegans, reveal the ketone body -hydroxybutyrate interacts directly with misfolded proteins, altering their solubility and structure so they can be cleared from the brain through the process of autophagy. The work hints at a tantalizing possibility -- ketone bodies as a global treatment to restore the integrity of the proteome, addressing one of the key hallmarks of aging.


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Can a Bidet Reduce Urinary Tract Infections in Seniors?

Could a bidet improve your older adult’s personal hygiene and comfort? Many Bidets explains how a bidet can make aRead More


The post Can a Bidet Reduce Urinary Tract Infections in Seniors? appeared first on DailyCaring.


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Antipsychotic medications don't always work the way they're supposed to

A study analyzed data from nearly 500,000 Canadian patients who lived in nursing homes across Canada between 2000 and 2022. It found that residents who were given antipsychotic medications showed a significant worsening of their behaviors. In fact, nearly 68 per cent of residents who used antipsychotics had more problems with their behavior during follow-up checks.


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Can everyday physical activity improve cognitive health in middle age?

Engaging in everyday physical activity has immediate benefits for brain health. Middle-aged people who participated in everyday movement showed improvement in cognitive processing speed equivalent to being four years younger, regardless of the activity's intensity.


http://dlvr.it/TGkqvg

Caregiver Holiday Stress Guide: 6 Top Tips for Managing Stress

Have a more pleasant holiday with our best caregiver stress tips Holidays are stressful enough, but when you add caregivingRead More


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Possible colon cancer vaccine target uncovered in bacteria

By comparing cancer incidence rates with genomic surveillance data, researchers suggest that higher rates of certain cancers in the UK and other countries may be linked to two bacterial strains. These strains are also among the most frequent causes of urinary tract infections.


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Largest-ever exome study offers blueprint for biomedical breakthroughs

Scientists have achieved a significant milestone generating a large collection of exome data, which include genes that code for proteins -- key to understanding health and disease.


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10 Top Holiday Gifts for Caregivers

Date published: 2024-12-9 This year, get the gifts you really want This holiday season, let family and friends know aboutRead More


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DNA damage is key factor in age-related macular degeneration

A research team has discovered that accumulated DNA damage in the retina is a key contributor to age-related macular degeneration and that targeting specific retinal cell types may lead to treatments that slow or stop progression.


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Researchers develop new saliva test to rapidly identify paracetamol overdose

A research team has developed a Mass Spectrometry technology-based technique to rapidly assess paracetamol levels from saliva.


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5 Worst Tech Gifts for Seniors (and What to Give Instead)

Date published: 2024-12-8 Technology gifts don’t always work out as planned Technology has brought many wonderful conveniences to everyday life. Read More


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Researchers use artificial intelligence to diagnose depression

Depression is one of the most common mental illnesses. As many as 280 million people worldwide are affected by this disease, which is why researchers have developed an artificial intelligence (AI) model that helps to identify depression based on both speech and brain neural activity. This multimodal approach, combining two different data sources, allows a more accurate and objective analysis of a person's emotional state, opening the door to a new phase of depression diagnosis.


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